In this issue of Research Round Up we have focused on recent research on TAND, TSC Associated Neuropsychiatric Disorders.

TAND Clusters

At TSA's TAND+ Conference in November, Professor Petrus de Vries presented on TAND and talked about his team's recent work identifying TAND levels and TAND clusters. The TAND clusters are:

Scholastic
Neuropsychological
Dysregulated behaviour
Overactive/impulsive
Eat/sleep
Mood/anxiety
Autism spectrum disorder-like

The (very clever and very complex) means by which the team identified the TAND clusters is detailed in this recent paper: Multivariate data analysis identifies natural clusters of Tuberous Sclerosis Complex Associated Neuropsychiatric Disorders (TAND) | Orphanet Journal of Rare Diseases | Full Text (biomedcentral.com)

For those who would like to know about TAND, including TAND levels and TAND clusters, the presentation by Professor Petrus de Vries is available on our website by clicking here.

View the TAND video

Autism Spectrum Disorder (ASD) and TAND

Autism spectrum disorder (ASD) is one of the most common TAND diagnoses, with previous research showing 30-50% of individuals with TSC meet the criteria for ASD, compared to 2% for the general population.

This study looked at developmental and behavioural features in infants with TSC by the time they were 36 months of age which might indicate higher suspicion for ASD.

Read more

DISCLAIMER

This information is intended to provide some insights into recent TSC-related research. It is not intended to, and it should not, constitute medical or other advice. Readers are warned not to take any action without first seeking medical advice.

FURTHER INFORMATION

Citations (and links where possible) to the full research articles/papers are included for those who would like to know more.

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